Exercise may not erase old memories, as some studies in animals have previously suggested.Running on an exercise wheel doesn’t make rats forget previous trips through an underwater maze, Ashok Shetty and colleagues report August 2 in the Journal of Neuroscience. Exercise or not, four weeks after learning how to find a hidden platform, rats seem to remember the location just fine, the team found.
The results conflict with two earlier papers that show that running triggers memory loss in some rodents by boosting the birth of new brain cells. Making new brain cells rejiggers memory circuits, and that can make it hard for animals to remember what they’ve learned, says Paul Frankland, a neuroscientist at the Hospital for Sick Children in Toronto. He has reported this phenomenon in mice, guinea pigs and degus (SN: 6/14/14, p. 7).
Maybe rats are the exception, he says, “but I’m not convinced.”In 2014, Frankland and colleagues reported that brain cell genesis clears out fearful memories in three different kinds of rodents. Two years later, Frankland’s team found similar results with spatial memories. After exercising, mice had trouble remembering the location of a hidden platform in a water maze, the team reported in February in Nature Communications. Again, Frankland and colleagues pinned the memory wipeout on brain cell creation — like a chalkboard eraser that brushes away old information. The wipe seemed to clear the way for new memories to form.
Shetty, a neuroscientist at Texas A&M Health Science Center in Temple, wondered if the results held true in rats, too. “Rats are quite different from mice,” he says. “Their biology is similar to humans.”
Using a water maze similar to Frankland’s, Shetty’s team taught two groups of rats how to find a hidden platform in eight training sessions over eight days. Then rats in just one of the groups exercised on a running wheel. Four weeks later, rats in both groups performed the same in the maze test — despite the fact that running rats had 1.5 to 2 times more newly born brain cells in the hippocampus, a skinny strip of tissue that’s thought to help form new memories.
夜上海最新论坛
These results and other memory tests “clearly showed that exercise did not interfere with memory recall,” Shetty says. And it’s likely that exercise doesn’t harm human memories either, he says.
Frankland says it’s possible that Shetty’s rats just learned the water maze too well. Shetty’s team trained their rodents for longer than Frankland’s team did, perhaps etching memories more deeply in the brain.
“The stronger the memory is, the harder it is going to be to erase it,” Frankland says.But he points out that erasing memories isn’t necessarily a bad thing. “People get hung up on this idea,” he says, but actually, clearing out old info from the brain — forgetting — is important. Without some sort of clearance process, “your memory is going to be full of junk.”
相关文章Exclusive: Hong Kong mutual benefit policy serves to complement rather than compete with potential partners: HKSAR Chief Executive
Editors Note: Hong Kong Special Administrative Region (HKSAR) Chief Executive, John Lee Ka-chiu (Lee), led a high-level delegation of 70 people to participate in the third Belt and Road Forum for International Cooperation held in Beijing from October 18 to 19. At the forum, he invited entrepreneurs to Hong Kong to set up belt and […]
Growing fondness: why are Arab youth increasingly drawn to China?A recent public opinion survey conducted in Dubai targeting Arab youth revealed that eight out of 10 respondents consider China an ally, marking the highest number of respondents to hold this view in four years. According to data from the United Nations Population Fund, the Arab region is characterized by a substantial youth population, with […]
China’s medical assistance boosts healthcare development in South Pacific region"For this surgery, we have prepared for more than half a year," Xiao Yuehai told the Global Times when talking about the first laparoscopic surgery carried out in Solomon Islands. Xiao is an urologist from the Affiliated Hospital of Guizhou Medical University (AHGMU) and a member of the second group of Chinese medical workers dispatched […]
Shake down under
还没有评论,来说两句吧...